Buy Domperidone (Motilium) online
How and where to order Motilium (Domperidone) 10 mg tablets online:
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|Forms:||Motilium (Domperidone) 10 mg tablets
|Type:||Motilium brand, Domperidone generic
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|Delivery:||Regular and express mail service
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Indications and usage:
Motilium (Domperidone) is used to treat the following conditions in children and adults:
nausea and vomiting
discomfort caused by a slow moving stomach known as gastroparesis. Symptoms include not being able to finish a meal, a feeling of being "too full" or bloated after a meal, a loss of appetite, feeling sick and maybe vomiting, or belching without relief.
Dosage and administration:
Motilium should be taken 15-30 minutes before meals and, if necessary, before retiring. If taken after meals, absorption is somewhat delayed.
1 tablet three to four times daily. The dose of domperidone should be the lowest effective dose for the individual situation (typically 30 mg/day). The dose may be increased, if necessary, to a maximum daily oral dose of 40 mg (1 tablet four times daily).
Usually, the maximum treatment duration should not exceed one week for the treatment of acute nausea and vomiting. If nausea and vomiting persists for longer than one week, patients should consult their physician. For other indications, the initial duration of treatment is up to four weeks. If treatment exceeds four weeks, patients should be re-evaluated and the need for continued treatment re-assessed. Domperidone (Motilium) tablets are unsuitable for use in adults and adolescents weighing less than 35 kg.
Dosage forms and strengt:
Motilium (Domperidone) film-coated tablet 10 mg.
Symptoms and signs
Overdose by domperidone has been reported primarily in infants and children. Symptoms of overdosage may include agitation, altered consciousness, convulsion, disorientation, somnolence and extrapyramidal reactions.
There is no specific antidote to domperidone. Anticholinergics, anti-Parkinsonian agents may be helpful in controlling the extrapyramidal reactions. Close observation and supportive therapy is recommended.
Motilium is contraindicated in the following situations:
Known hypersensitivity to domperidone or any of the excipients.
Prolactin-releasing pituitary tumour (prolactinoma).
Use in children under 2 years of age.
Co-administration with potent CYP3A4 inhibitors has been shown to increase domperidone concentrations to the point where QT interval prolongation may occur. Examples of potent CYP3A4 inhibitors include some azole antifungals (eg, intraconazole, voriconazole, posaconzazole), some macrolide antibiotics (eg, clarithromycin, telithromycin), and some protease inhibitors (ritonavir, saquinavir, telaprevir).
Co-administration with medicines that prolong the QTc interval.
Motilium should not be used whenever stimulation of gastrointestinal motility might be dangerous such as in the presence of gastrointestinal haemorrhage, mechanical obstruction, or perforation.
In patients with moderate or severe hepatic impairment.
Warnings and precautions:
Cardiovascular effects: Motilium (Domperidone) should be used with caution in older patients or those with current or history of cardiac disease.
Drug interaction potential: the main metabolic pathway of domperidone is through CYP3A4.
Intolerance to lactose: the film-coated tablets contain lactose and may be unsuitable for patients with lactose intolerance, galactosemia or glucose/galactose malabsorption.
Prolactin levels: Motilium produces an increase in plasma prolactin.
Renal impairment: since the elimination half-life of domperidone is prolonged in severe renal impairment, the dosing frequency of Motilium should to be reduced to once or twice daily depending on the severity of the impairment.
Hepatic Impairment: this medication is contraindicated for patients with moderate or severe hepatic impairment.
Infants: Domperidone (Motilium) tablets are unsuitable for use in children < 2 years of age.
Adverse reactions, side effects:
The most commonly reported adverse reactions of domperidone:
uncontrollable movements of the face or arms and legs, excessive trembling, excessive muscle stiffness or muscle spasm
irregular or no menstrual period
unusual secretion of breast milk or decrease in sex drive in men or women
breast tenderness or breast enlargement in men and women.
To report suspected side effects of Motilium (Domperidone) pills contact Janssen pharmaceutical company or your local FDA.
Medicines that prolong the QTc interval
Potent and moderate CYP3A4 inhibitors
Co-Trimoxazole (Bactrim, Septra)
Use in specific populations:
There are limited post-marketing data on the use of domperidone in pregnant women. A study in rats has shown reproductive toxicity at a high, maternally toxic dose. The potential risk for humans is unknown. Therefore, Motilium should only be used during pregnancy when justified by the anticipated therapeutic benefit.
The amount of domperidone that could be ingested by an infant through breast milk is low. The maximal relative infant dose (%) is estimated to be about 0.1% of the maternal weight-adjusted dosage. It is not known whether this is harmful to the newborn. Therefore breastfeeding is not recommended for women who are taking Motilium tablets.
Effects on ability to drive and use machines
Dizziness and somnolence have been observed following use of domperidone. Therefore, patients should be advised not to drive or use machinery or engage in other activities requiring mental alertness and coordination until they have established how Motilium (Domperidone) affects them.
Where to buy domperidone online:
To purchase Motilium (Domperidone) 10 mg tablets from reliable online pharmacies and drugstores at low prices please use resources described above on this webpage.
Here is a list of popular medications containing domperidone as a main active pharmaceutical ingredient; their trade names, forms, doses, companies - manufacturers, distributors, suppliers, researchers and developers:
|Trade name of the drug
||Pharmaceutical forms and doses
||Tablets, Film-Coated; Oral; Domperidone 20 mg
||Suppositories; Rectal; Domperidone 30 mgSuppositories; Rectal; Domperidone 60 mgSuspension; Oral; Domperidone 5 mg / 5 mlTablets, Film-Coated; Oral; Domperidone 10 mg
||JanssenJohnson & Johnson
||Drops; Oral; Domperidone 10 mg / mlSuspension; Oral; Domperidone 5 mg / 5 mlTablets, Dispersible; Oral; Domperidone 5 mgTablets, Dispersible; Oral; Domperidone 10 mgTablets; Oral; Domperidone 10 mgTablets; Oral; Domperidone 30 mg
||Tablets, Dispersible; Oral; Domperidone 10 mg
||Injectable; Injection; Domperidone 4 mg / 3 mlInjectable; Injection; Domperidone 10 mg / 3 mlSuspension; Oral; Domperidone 10 mg / mlTablets; Oral; Domperidone 10 mg
||Drops; Oral; Domperidone 10 mg / mlGranules, Effervescent; Oral; Domperidone 10 mgInjectable; Injection; Domperidone 2 mg / mlInjectable; Injection; Domperidone 5 mg / mlSuppositories; Rectal; Domperidone 10 mgSuppositories; Rectal; Domperidone 30 mgSuppositories; Rectal; Domperidone 60 mgSuspension; Oral; Domperidone 5 mg / 5 mlSyrup; Oral; Domperidone 5 mg / 5 mlTablets, Film-Coated; Oral; Domperidone 10 mgTablets, Orally Disintegrating; Oral; Domperidone 10 mgTablets; Oral; Domperidone 10 mg
||JanssenAltana PharmaCatalentDKSHDoncaster Pharmaceuticals GroupDr. Esteve LaboratoriosFour StarJohnson & JohnsonLandmark PharmaOrtho McNeil PharmaceuticalsMedicemNeoFarma PharmaceuticalsS & M MedicalPharmaghreb LaboratoiresSanofi-AventisS.C. TerapiaTakeda PharmaceuticalThe Glory MedicinaWinthrop PharmaceuticalsZentivaZuellig Pharma
||Tablets; Sublingual; Domperidone 10 mg
||Drops; Oral; Domperidone 1 mg / mlSuppositories; Rectal; Domperidone 10 mgSuppositories; Rectal; Domperidone 30 mgSuppositories; Rectal; Domperidone 60 mgSuspension; Oral; Domperidone 5 mg / 5 mlSyrup; Oral; Domperidone 5 mg / 5 mlTablets, Dispersible; Oral; Domperidone 10 mgTablets; Oral; Domperidone 10 mgTablets; Oral; Domperidone 30 mg
||Medley PharmaceuticalsAmbica International Trading CorporationGlaxoSmithKlineRoyal DistributionSharif PharmaceuticalsSuprakare
||Granules, Effervescent; Oral; Domperidone 10 mgPowder for Syrup; Oral; Domperidone 10 mgSuspension; Oral; Domperidone 5 mg / 5 mlTablets; Oral; Domperidone 5 mgTablets; Oral; Domperidone 10 mg
||Drops; Oral; Domperidone 1 mg / mlDrops; Oral; Domperidone 5 mg / mlSuspension; Oral; Domperidone 5 mg / 5 mlTablets, Dispersible; Oral; Domperidone 10 mgTablets, Film-Coated; Oral; Domperidone 10 mgTablets; Oral; Domperidone 10 mgTablets, Sustained Release; Oral; Domperidone 30 mg
||CiplaDanas PharmaceuticalsGracia Pharmindo