How and where to order Domperidone (Motilium) 10 mg tablets online on Intermountain Pediatric Society website:
|Prices:||from $0.23 per pill
|Discount:||10% coupon: DFHDCC
|Forms:||Motilium (Domperidone) 10 mg tablets
|Type:||Motilium brand, Domperidone generic
|Payment:||Visa, Mastercard, AmEx, E-Check (ACH), Bitcoin
|Delivery:||Regular and express mail service
|Shipping:||Worldwide, including USA, UK, Europe, Canada, Australia
Domperidone (trade names include Motilium, Apo-Domperidone, Biperidys, Cilroton, Dom-DT, Domperidon Stada, Domperidona, Domperidone Arrow, Domstal, Endone, Domperidone Mylan, Euciton, Gastractiv, Domperidone Sandoz, Motilium Lingual Gastrosan, Domperidone Teva, Motilium Lingual, Motinorm, Nauzelin, Oroperidys, Ratio-Domperidone, Tilium, Vometa, Vomistop) is a medication for gastrointestinal tract diseases from propulsives pharmacological group. This medicine is used for the treatment of nausea and vomiting (including associated with acute migraine), discomfort caused by a slow moving stomach known as gastroparesis by increasing movements or contractions of the stomach and bowel, fullness or bloating and regurgitation of stomach contents (reflux or heartburn), delayed gastric emptying of functional origin with gastro-oesophageal reflux and/or dyspepsia, pediatric reflux, as an anti-emetic in patients receiving cytostatic and radiation therapy, to relieve gastrointestinal symptoms in Parkinson's disease, to promote lactation by release of prolactin. Domperidone also facilitates radiological examination of the upper gastrointestinal tract. It works by blocking the action of a chemical messenger in the brain which causes the feeling of nausea and vomiting, as well as increasing the movement or contractions of the stomach and intestines, allowing food to move more easily through the stomach.
Pharmacological and medical categories:
Antiflatulents and anti-inflammatories
Anti nausea drugs
Anti vomiting medications
Gastric prokinetic agents
Peripherally selective dopamine D2-receptor antagonists
Veterinary, pet meds
A - Alimentary tract and metabolism
A03 - Drugs for functional gastrointestinal disorders
A03F - Propulsives
A03FA - Propulsives
A03FA03 - Domperidone
Radiation therapy - D
Parkinson's disease - G20
Migraine - G43
Gastro-oesophageal reflux disease - K21
Dyspepsia - K30
Other diseases of stomach and duodenum - K31
Gastroparesis - K31.84
Other disorders of breast and disorders of lactation associated with pregnancy and the puerperium - O92
Other perinatal digestive system disorders - P78
Newborn esophageal reflux - P78.83
Feeding problems of newborn - P92
Abdominal and pelvic pain - R10
Nausea and vomiting - R11
Heartburn - R12
Flatulence and related conditions - R14
Indications and usage:
Motilium (Domperidone) is used to treat the following conditions in children and adults:
nausea and vomiting
discomfort caused by a slow moving stomach known as gastroparesis. Symptoms include not being able to finish a meal, a feeling of being "too full" or bloated after a meal, a loss of appetite, feeling sick and maybe vomiting, or belching without relief.
Dosage and administration:
Motilium should be taken 15-30 minutes before meals and, if necessary, before retiring. If taken after meals, absorption is somewhat delayed.
1 tablet three to four times daily. The dose of domperidone should be the lowest effective dose for the individual situation (typically 30 mg/day). The dose may be increased, if necessary, to a maximum daily oral dose of 40 mg (1 tablet four times daily).
Usually, the maximum treatment duration should not exceed one week for the treatment of acute nausea and vomiting. If nausea and vomiting persists for longer than one week, patients should consult their physician. For other indications, the initial duration of treatment is up to four weeks. If treatment exceeds four weeks, patients should be re-evaluated and the need for continued treatment re-assessed. Domperidone (Motilium) tablets are unsuitable for use in adults and adolescents weighing less than 35 kg.
Dosage forms and strengt:
Motilium (Domperidone) film-coated tablet 10 mg.
Symptoms and signs
Overdose by domperidone has been reported primarily in infants and children. Symptoms of overdosage may include agitation, altered consciousness, convulsion, disorientation, somnolence and extrapyramidal reactions.
There is no specific antidote to domperidone. Anticholinergics, anti-Parkinsonian agents may be helpful in controlling the extrapyramidal reactions. Close observation and supportive therapy is recommended.
Motilium is contraindicated in the following situations:
Known hypersensitivity to domperidone or any of the excipients.
Prolactin-releasing pituitary tumour (prolactinoma).
Use in children under 2 years of age.
Co-administration with potent CYP3A4 inhibitors has been shown to increase domperidone concentrations to the point where QT interval prolongation may occur. Examples of potent CYP3A4 inhibitors include some azole antifungals (eg, intraconazole, voriconazole, posaconzazole), some macrolide antibiotics (eg, clarithromycin, telithromycin), and some protease inhibitors (ritonavir, saquinavir, telaprevir).
Co-administration with medicines that prolong the QTc interval.
Motilium should not be used whenever stimulation of gastrointestinal motility might be dangerous such as in the presence of gastrointestinal haemorrhage, mechanical obstruction, or perforation.
In patients with moderate or severe hepatic impairment.
Warnings and precautions:
Cardiovascular effects: Motilium (Domperidone) should be used with caution in older patients or those with current or history of cardiac disease.
Drug interaction potential: the main metabolic pathway of domperidone is through CYP3A4.
Intolerance to lactose: the film-coated tablets contain lactose and may be unsuitable for patients with lactose intolerance, galactosemia or glucose/galactose malabsorption.
Prolactin levels: Motilium produces an increase in plasma prolactin.
Renal impairment: since the elimination half-life of domperidone is prolonged in severe renal impairment, the dosing frequency of Motilium should to be reduced to once or twice daily depending on the severity of the impairment.
Hepatic Impairment: this medication is contraindicated for patients with moderate or severe hepatic impairment.
Infants: Domperidone (Motilium) tablets are unsuitable for use in children < 2 years of age.
Adverse reactions, side effects:
The most commonly reported adverse reactions of domperidone:
uncontrollable movements of the face or arms and legs, excessive trembling, excessive muscle stiffness or muscle spasm
irregular or no menstrual period
unusual secretion of breast milk or decrease in sex drive in men or women
breast tenderness or breast enlargement in men and women.
To report suspected side effects of Motilium (Domperidone) pills contact Janssen pharmaceutical company or your local FDA.
Medicines that prolong the QTc interval
Potent and moderate CYP3A4 inhibitors
Use in specific populations:
There are limited post-marketing data on the use of domperidone in pregnant women. A study in rats has shown reproductive toxicity at a high, maternally toxic dose. The potential risk for humans is unknown. Therefore, Motilium should only be used during pregnancy when justified by the anticipated therapeutic benefit.
The amount of domperidone that could be ingested by an infant through breast milk is low. The maximal relative infant dose (%) is estimated to be about 0.1% of the maternal weight-adjusted dosage. It is not known whether this is harmful to the newborn. Therefore breastfeeding is not recommended for women who are taking Motilium tablets.
Effects on ability to drive and use machines
Dizziness and somnolence have been observed following use of domperidone. Therefore, patients should be advised not to drive or use machinery or engage in other activities requiring mental alertness and coordination until they have established how Motilium (Domperidone) affects them.
B2 - Australia
C - United States (Risk cannot be ruled out)
Salts and other forms:
Synonyms, international and chemical names:
Brands, generics, trade names:
Apo-Domperidone - Apotex, Nhan Tam, Pharmaforte
Biperidys - Pierre Fabre
Cilroton - Janssen
Cinet - Medinfar Laboratorio, Friday's Pharma
Damelium - Actavis, Farmaceutisch Analytisch Laboratorium Duiven
Digestivo Giuliani - Giuliani
Domcolic - Zydus Cadila
Dom-DT - Morepen Laboratories
Domedon - Tempo Scan Pacific
Domerid - Rowa Pharmaceuticals
Domidon - Gry-Pharma
Dompenyl - Kyowa Hakko, Korea United Pharmaceutical, Pharma 3, Ziwell Medical
Domperidon - Sandoz, Stada, Zota Healthcare
Domperidona - Biosano Laboratorios, Chile Laboratorios
Domperidone - Arrow Generiques, Biogaran, EG Labo, Mylan, Sandoz, Teva, Zydus Pharmaceuticals
Domperon - Cadila Pharmaceuticals, IRM Pharma, Zydus Cadila
Dompil - Shinpoong Daewoo Pharma
Domstal - Torrent Pharmaceuticals
Domstal MT - Torrent Pharmaceuticals
Endone - Zenon Healthcare
Euciton - Roux-Ocefa Laboratorios
Galflux - Guardian Pharmatama
Gastractiv - Johnson & Johnson, Ethnor
Gastrodin - Euro Generics
Gastronorm - Janssen
Mirax-M - Berlin Pharmaceutical Industry
Molax-M - Siam Pharmaceutical
Motidom - T.O. Chemicals, Medley Pharmaceuticals
Motilium - Janssen, Johnson & Johnson, Ortho McNeil Pharmaceuticals, Sanofi-Aventis
Motilium Babies - Janssen
Motilium Lingual - Janssen
Motilium Lingual Gastrosan - Janssen
Motilium-M - Janssen, DKSH, Johnson & Johnson, Zuellig Pharma
Motilyo - Janssen
Motinorm - Medley Pharmaceuticals
Mylan-Domperidone - Mylan
Nauzelin - Janssen
Oroperidys - Pierre Fabre
Peridal - Medley Industria Farmaceutica
Peridys - Pierre Fabre
PMS-Domperidone - Pharmascience
Prokinin - Tabuk Pharmaceuticals
Ratio-Domperidone - Ratiopharm, Teva
Seronex - Productos Medix
Siligaz - Prater Laboratorio
Teva-Domperidone - Teva
Tilium - Janssen
Vesperum - Ifars Pharmaceutical Laboratories
Vomerin - Soho Industri Pharmasi
Vometa - Dexa Medica Pharm & Chem, Getz Brothers
Vomidon - Be-Tabs Pharmaceuticals, Daksh Phramaceuticals
Vomidone - Pharos
Vominorm - Suzikem Drugs
Vomistop - Cipla
Vomitas - Kalbe Farma
Vosedon - Sanbe Farma
Zilium - Wolfs Laboratoria, Kela
Zydom - Zota Pharmaceuticals
APIs used in medicine in combinations with domperidone:
Here is a list of popular medications containing domperidone as a main active pharmaceutical ingredient; their trade names, forms, doses, companies - manufacturers, distributors, suppliers, researchers and developers:
|Trade name of the drug
||Pharmaceutical forms and doses
||Tablets, Film-Coated; Oral; Domperidone 20 mg
||Suppositories; Rectal; Domperidone 30 mgSuppositories; Rectal; Domperidone 60 mgSuspension; Oral; Domperidone 5 mg / 5 mlTablets, Film-Coated; Oral; Domperidone 10 mg
||JanssenJohnson & Johnson
||Drops; Oral; Domperidone 10 mg / mlSuspension; Oral; Domperidone 5 mg / 5 mlTablets, Dispersible; Oral; Domperidone 5 mgTablets, Dispersible; Oral; Domperidone 10 mgTablets; Oral; Domperidone 10 mgTablets; Oral; Domperidone 30 mg
||Tablets, Dispersible; Oral; Domperidone 10 mg
||Injectable; Injection; Domperidone 4 mg / 3 mlInjectable; Injection; Domperidone 10 mg / 3 mlSuspension; Oral; Domperidone 10 mg / mlTablets; Oral; Domperidone 10 mg
||Drops; Oral; Domperidone 10 mg / mlGranules, Effervescent; Oral; Domperidone 10 mgInjectable; Injection; Domperidone 2 mg / mlInjectable; Injection; Domperidone 5 mg / mlSuppositories; Rectal; Domperidone 10 mgSuppositories; Rectal; Domperidone 30 mgSuppositories; Rectal; Domperidone 60 mgSuspension; Oral; Domperidone 5 mg / 5 mlSyrup; Oral; Domperidone 5 mg / 5 mlTablets, Film-Coated; Oral; Domperidone 10 mgTablets, Orally Disintegrating; Oral; Domperidone 10 mgTablets; Oral; Domperidone 10 mg
||JanssenAltana PharmaCatalentDKSHDoncaster Pharmaceuticals GroupDr. Esteve LaboratoriosFour StarJohnson & JohnsonLandmark PharmaOrtho McNeil PharmaceuticalsMedicemNeoFarma PharmaceuticalsS & M MedicalPharmaghreb LaboratoiresSanofi-AventisS.C. TerapiaTakeda PharmaceuticalThe Glory MedicinaWinthrop PharmaceuticalsZentivaZuellig Pharma
||Tablets; Sublingual; Domperidone 10 mg
||Drops; Oral; Domperidone 1 mg / mlSuppositories; Rectal; Domperidone 10 mgSuppositories; Rectal; Domperidone 30 mgSuppositories; Rectal; Domperidone 60 mgSuspension; Oral; Domperidone 5 mg / 5 mlSyrup; Oral; Domperidone 5 mg / 5 mlTablets, Dispersible; Oral; Domperidone 10 mgTablets; Oral; Domperidone 10 mgTablets; Oral; Domperidone 30 mg
||Medley PharmaceuticalsAmbica International Trading CorporationGlaxoSmithKlineRoyal DistributionSharif PharmaceuticalsSuprakare
||Granules, Effervescent; Oral; Domperidone 10 mgPowder for Syrup; Oral; Domperidone 10 mgSuspension; Oral; Domperidone 5 mg / 5 mlTablets; Oral; Domperidone 5 mgTablets; Oral; Domperidone 10 mg
||Drops; Oral; Domperidone 1 mg / mlDrops; Oral; Domperidone 5 mg / mlSuspension; Oral; Domperidone 5 mg / 5 mlTablets, Dispersible; Oral; Domperidone 10 mgTablets, Film-Coated; Oral; Domperidone 10 mgTablets; Oral; Domperidone 10 mgTablets, Sustained Release; Oral; Domperidone 30 mg
||CiplaDanas PharmaceuticalsGracia Pharmindo
Domperidone main article on Wikipedia: https://en.wikipedia.org/wiki/Domperidone
Domperidone compound on PubChem: https://pubchem.ncbi.nlm.nih.gov/compound/Domperidone
Domperidone medicine on DrugBank: https://go.drugbank.com/drugs/DB01184
Domperidone containing drugs on Drugs-About.com: https://drugs-about.com/ing/domperidone.html
Domperidone for sale on Pharma Doctor: https://pharma-doctor.com/domperidone.html
Motilium (Domperidone) 10 mg film-coated tablets prescribing information from MedSafe (revised 19 November 2020): https://www.medsafe.govt.nz/profs/Datasheet/m/motiliumtab.pdf
Motilium (Domperidone) 10 mg tablets product information from The Therapeutic Goods Administration (revised 04 September 2020): https://www.ebs.tga.gov.au/ebs/picmi/...
Motilium (Domperidone) tablets consumer medicine information from The Therapeutic Goods Administration (revised August 2020): https://www.ebs.tga.gov.au/ebs/picmi/...
Motilium (Domperidone) 10 mg film-coated tablets summary of product characteristics from Medicines.org.uk (revised 11/09/2020): https://www.medicines.org.uk/emc/product/4177/smpc
Motilium (Domperidone) 10 mg film-coated tablets package information leaflet on Medicines.org.uk (revised March 2020): https://www.medicines.org.uk/emc/files/pil.4177.pdf
Revised: August 2021
Home | About IPS | Officers | Committees & Special Areas | Membership | Legislative Update | Newsletter | Save the Date | Pediatric Managers Group
Copyright © 2001 - 2021 Intermountain Pediatric Society / American Academy of Pediatrics Utah Chapter. All Rights Reserved.