Domperidone Online



How and where to order Domperidone (Motilium) 10 mg tablets online on Intermountain Pediatric Society website:

Shop:DFH PHARMACY
Stores:PHARMA DOCTOR
Prices:from $0.23 per pill
Discount:10% coupon: DFHDCC
Forms:Motilium (Domperidone) 10 mg tablets
Quantity:30-360 pills
Type:Motilium brand, Domperidone generic
Payment:Visa, Mastercard, AmEx, E-Check (ACH), Bitcoin
Delivery:Regular and express mail service
Shipping:Worldwide, including USA, UK, Europe, Canada, Australia


Domperidone (trade names include Motilium, Apo-Domperidone, Biperidys, Cilroton, Dom-DT, Domperidon Stada, Domperidona, Domperidone Arrow, Domstal, Endone, Domperidone Mylan, Euciton, Gastractiv, Domperidone Sandoz, Motilium Lingual Gastrosan, Domperidone Teva, Motilium Lingual, Motinorm, Nauzelin, Oroperidys, Ratio-Domperidone, Tilium, Vometa, Vomistop) is a medication for gastrointestinal tract diseases from propulsives pharmacological group. This medicine is used for the treatment of nausea and vomiting (including associated with acute migraine), discomfort caused by a slow moving stomach known as gastroparesis by increasing movements or contractions of the stomach and bowel, fullness or bloating and regurgitation of stomach contents (reflux or heartburn), delayed gastric emptying of functional origin with gastro-oesophageal reflux and/or dyspepsia, pediatric reflux, as an anti-emetic in patients receiving cytostatic and radiation therapy, to relieve gastrointestinal symptoms in Parkinson's disease, to promote lactation by release of prolactin. Domperidone also facilitates radiological examination of the upper gastrointestinal tract. It works by blocking the action of a chemical messenger in the brain which causes the feeling of nausea and vomiting, as well as increasing the movement or contractions of the stomach and intestines, allowing food to move more easily through the stomach.


Motilium (Domperidone) 10 mg tablets


Related medications:

  • Alizapride (Litican)
  • Bisacodyl (Dulcolax)
  • Bromopride (Valopride)
  • Butylscopolamine (Buscopan)
  • Cisapride (Propulsid)
  • Clebopride (Clanzol)
  • Dimenhydrinate (Dramamine)
  • Esdomperidone (Nexium)
  • Famotidine (Pepcid)
  • Itopride (Ganaton)
  • Lansoprazole (Prevacid)
  • Loperamide (Imodium)
  • Mebeverine (Colofac)
  • Meclizine (Antivert)
  • Mesalamine (Asacol)
  • Metoclopramide (Reglan)
  • Omeprazole (Prilosec)
  • Ondansetron (Zofran)
  • Pantoprazole (Protonix)
  • Rabeprazole (Aciphex)
  • Ranitidine (Zantac)
  • Sucralfate (Carafate)
  • Sumatriptan (Imitrex)


    Pharmacological and medical categories:

  • Antiemetics
  • Antiflatulents and anti-inflammatories
  • Anti nausea drugs
  • Anti vomiting medications
  • Galactagogue
  • Gastric prokinetic agents
  • Gastroprokinetic agents
  • GIT regulators
  • Peripherally selective dopamine D2-receptor antagonists
  • Prokinetic agents
  • Veterinary, pet meds


    ATC codes:

  • A - Alimentary tract and metabolism
  • A03 - Drugs for functional gastrointestinal disorders
  • A03F - Propulsives
  • A03FA - Propulsives
  • A03FA03 - Domperidone


    ICD-10 codes:

  • Radiation therapy - D
  • Parkinson's disease - G20
  • Migraine - G43
  • Gastro-oesophageal reflux disease - K21
  • Dyspepsia - K30
  • Other diseases of stomach and duodenum - K31
  • Gastroparesis - K31.84
  • Other disorders of breast and disorders of lactation associated with pregnancy and the puerperium - O92
  • Other perinatal digestive system disorders - P78
  • Newborn esophageal reflux - P78.83
  • Feeding problems of newborn - P92
  • Abdominal and pelvic pain - R10
  • Nausea and vomiting - R11
  • Heartburn - R12
  • Flatulence and related conditions - R14


    Indications and usage:

    Motilium (Domperidone) is used to treat the following conditions in children and adults:

  • nausea and vomiting
  • discomfort caused by a slow moving stomach known as gastroparesis. Symptoms include not being able to finish a meal, a feeling of being "too full" or bloated after a meal, a loss of appetite, feeling sick and maybe vomiting, or belching without relief.


    Dosage and administration:

    Motilium should be taken 15-30 minutes before meals and, if necessary, before retiring. If taken after meals, absorption is somewhat delayed.

    1 tablet three to four times daily. The dose of domperidone should be the lowest effective dose for the individual situation (typically 30 mg/day). The dose may be increased, if necessary, to a maximum daily oral dose of 40 mg (1 tablet four times daily).

    Usually, the maximum treatment duration should not exceed one week for the treatment of acute nausea and vomiting. If nausea and vomiting persists for longer than one week, patients should consult their physician. For other indications, the initial duration of treatment is up to four weeks. If treatment exceeds four weeks, patients should be re-evaluated and the need for continued treatment re-assessed. Domperidone (Motilium) tablets are unsuitable for use in adults and adolescents weighing less than 35 kg.


    Dosage forms and strengt:

    Motilium (Domperidone) film-coated tablet 10 mg.


    Overdosage:

    Symptoms and signs

    Overdose by domperidone has been reported primarily in infants and children. Symptoms of overdosage may include agitation, altered consciousness, convulsion, disorientation, somnolence and extrapyramidal reactions.

    Treatment

    There is no specific antidote to domperidone. Anticholinergics, anti-Parkinsonian agents may be helpful in controlling the extrapyramidal reactions. Close observation and supportive therapy is recommended.


    Contraindications:

    Motilium is contraindicated in the following situations:

  • Known hypersensitivity to domperidone or any of the excipients.
  • Prolactin-releasing pituitary tumour (prolactinoma).
  • Use in children under 2 years of age.
  • Co-administration with potent CYP3A4 inhibitors has been shown to increase domperidone concentrations to the point where QT interval prolongation may occur. Examples of potent CYP3A4 inhibitors include some azole antifungals (eg, intraconazole, voriconazole, posaconzazole), some macrolide antibiotics (eg, clarithromycin, telithromycin), and some protease inhibitors (ritonavir, saquinavir, telaprevir).
  • Co-administration with medicines that prolong the QTc interval.
  • Motilium should not be used whenever stimulation of gastrointestinal motility might be dangerous such as in the presence of gastrointestinal haemorrhage, mechanical obstruction, or perforation.
  • In patients with moderate or severe hepatic impairment.


    Warnings and precautions:

  • Cardiovascular effects: Motilium (Domperidone) should be used with caution in older patients or those with current or history of cardiac disease.
  • Drug interaction potential: the main metabolic pathway of domperidone is through CYP3A4.
  • Intolerance to lactose: the film-coated tablets contain lactose and may be unsuitable for patients with lactose intolerance, galactosemia or glucose/galactose malabsorption.
  • Prolactin levels: Motilium produces an increase in plasma prolactin.
  • Renal impairment: since the elimination half-life of domperidone is prolonged in severe renal impairment, the dosing frequency of Motilium should to be reduced to once or twice daily depending on the severity of the impairment.
  • Hepatic Impairment: this medication is contraindicated for patients with moderate or severe hepatic impairment.
  • Infants: Domperidone (Motilium) tablets are unsuitable for use in children < 2 years of age.


    Adverse reactions, side effects:

    The most commonly reported adverse reactions of domperidone:

  • uncontrollable movements of the face or arms and legs, excessive trembling, excessive muscle stiffness or muscle spasm
  • irregular or no menstrual period
  • unusual secretion of breast milk or decrease in sex drive in men or women
  • breast tenderness or breast enlargement in men and women.

    To report suspected side effects of Motilium (Domperidone) pills contact Janssen pharmaceutical company or your local FDA.


    Drug interactions:

  • Medicines that prolong the QTc interval
  • Potent and moderate CYP3A4 inhibitors


    Use in specific populations:

    Pregnancy

    There are limited post-marketing data on the use of domperidone in pregnant women. A study in rats has shown reproductive toxicity at a high, maternally toxic dose. The potential risk for humans is unknown. Therefore, Motilium should only be used during pregnancy when justified by the anticipated therapeutic benefit.

    Lactation

    The amount of domperidone that could be ingested by an infant through breast milk is low. The maximal relative infant dose (%) is estimated to be about 0.1% of the maternal weight-adjusted dosage. It is not known whether this is harmful to the newborn. Therefore breastfeeding is not recommended for women who are taking Motilium tablets.

    Effects on ability to drive and use machines

    Dizziness and somnolence have been observed following use of domperidone. Therefore, patients should be advised not to drive or use machinery or engage in other activities requiring mental alertness and coordination until they have established how Motilium (Domperidone) affects them.


    Pregnancy categories:

  • B2 - Australia
  • C - United States (Risk cannot be ruled out)


    Salts and other forms:

  • Domperidone Base
  • Domperidone Hydrochloride
  • Domperidone Maleate


    Synonyms, international and chemical names:

  • Domperidon
  • Domperidona
  • Domperidone HCl
  • Domperidoni
  • Domperidoni Maleas
  • Domperidonmaleat
  • Domperidono
  • Domperidonum
  • Dompiridone


    Brands, generics, trade names:

  • Apo-Domperidone - Apotex, Nhan Tam, Pharmaforte
  • Biperidys - Pierre Fabre
  • Cilroton - Janssen
  • Cinet - Medinfar Laboratorio, Friday's Pharma
  • Damelium - Actavis, Farmaceutisch Analytisch Laboratorium Duiven
  • Digestivo Giuliani - Giuliani
  • Domcolic - Zydus Cadila
  • Dom-DT - Morepen Laboratories
  • Domedon - Tempo Scan Pacific
  • Domerid - Rowa Pharmaceuticals
  • Domidon - Gry-Pharma
  • Dompenyl - Kyowa Hakko, Korea United Pharmaceutical, Pharma 3, Ziwell Medical
  • Domperidon - Sandoz, Stada, Zota Healthcare
  • Domperidona - Biosano Laboratorios, Chile Laboratorios
  • Domperidone - Arrow Generiques, Biogaran, EG Labo, Mylan, Sandoz, Teva, Zydus Pharmaceuticals
  • Domperon - Cadila Pharmaceuticals, IRM Pharma, Zydus Cadila
  • Dompil - Shinpoong Daewoo Pharma
  • Domstal - Torrent Pharmaceuticals
  • Domstal MT - Torrent Pharmaceuticals
  • Endone - Zenon Healthcare
  • Euciton - Roux-Ocefa Laboratorios
  • Galflux - Guardian Pharmatama
  • Gastractiv - Johnson & Johnson, Ethnor
  • Gastrodin - Euro Generics
  • Gastronorm - Janssen
  • Mirax-M - Berlin Pharmaceutical Industry
  • Molax-M - Siam Pharmaceutical
  • Motidom - T.O. Chemicals, Medley Pharmaceuticals
  • Motilium - Janssen, Johnson & Johnson, Ortho McNeil Pharmaceuticals, Sanofi-Aventis
  • Motilium Babies - Janssen
  • Motilium Lingual - Janssen
  • Motilium Lingual Gastrosan - Janssen
  • Motilium-M - Janssen, DKSH, Johnson & Johnson, Zuellig Pharma
  • Motilyo - Janssen
  • Motinorm - Medley Pharmaceuticals
  • Mylan-Domperidone - Mylan
  • Nauzelin - Janssen
  • Oroperidys - Pierre Fabre
  • Peridal - Medley Industria Farmaceutica
  • Peridys - Pierre Fabre
  • PMS-Domperidone - Pharmascience
  • Prokinin - Tabuk Pharmaceuticals
  • Ratio-Domperidone - Ratiopharm, Teva
  • Seronex - Productos Medix
  • Siligaz - Prater Laboratorio
  • Teva-Domperidone - Teva
  • Tilium - Janssen
  • Vesperum - Ifars Pharmaceutical Laboratories
  • Vomerin - Soho Industri Pharmasi
  • Vometa - Dexa Medica Pharm & Chem, Getz Brothers
  • Vomidon - Be-Tabs Pharmaceuticals, Daksh Phramaceuticals
  • Vomidone - Pharos
  • Vominorm - Suzikem Drugs
  • Vomistop - Cipla
  • Vomitas - Kalbe Farma
  • Vosedon - Sanbe Farma
  • Zilium - Wolfs Laboratoria, Kela
  • Zydom - Zota Pharmaceuticals


    APIs used in medicine in combinations with domperidone:

  • Acetaminophen
  • Alprazolam
  • Betahistine
  • Bile Salts
  • Bromazepam
  • Chlorpheniramine
  • Cinnarizine
  • Clorazepate
  • Dehydrocholic Acid
  • Dexrabeprazole
  • Dicyclomine
  • Dimethicone
  • Esomeprazole
  • Famotidine
  • Flunarizine
  • Ilaprazole
  • Lansoprazole
  • Lafutidine
  • Magaldrate
  • Metamizole
  • Methylpolysiloxane
  • Naproxen
  • Omeprazole
  • Pancreatin
  • Pantoprazole
  • Pseudoephedrine
  • Rabeprazole
  • Ranitidine
  • Serrapeptase
  • Simethicone
  • Sucralfate
  • Tramadol


    Here is a list of popular medications containing domperidone as a main active pharmaceutical ingredient; their trade names, forms, doses, companies - manufacturers, distributors, suppliers, researchers and developers:

    Trade name of the drug Pharmaceutical forms and doses Companies
    Biperidys
  • Tablets, Film-Coated; Oral; Domperidone 20 mg
  • Pierre Fabre
  • Cilroton
  • Suppositories; Rectal; Domperidone 30 mg
  • Suppositories; Rectal; Domperidone 60 mg
  • Suspension; Oral; Domperidone 5 mg / 5 ml
  • Tablets, Film-Coated; Oral; Domperidone 10 mg
  • Janssen
  • Johnson & Johnson
  • Domstal
  • Drops; Oral; Domperidone 10 mg / ml
  • Suspension; Oral; Domperidone 5 mg / 5 ml
  • Tablets, Dispersible; Oral; Domperidone 5 mg
  • Tablets, Dispersible; Oral; Domperidone 10 mg
  • Tablets; Oral; Domperidone 10 mg
  • Tablets; Oral; Domperidone 30 mg
  • Torrent Pharmaceuticals
  • Endone
  • Tablets, Dispersible; Oral; Domperidone 10 mg
  • Zenon Healthcare
  • Euciton
  • Injectable; Injection; Domperidone 4 mg / 3 ml
  • Injectable; Injection; Domperidone 10 mg / 3 ml
  • Suspension; Oral; Domperidone 10 mg / ml
  • Tablets; Oral; Domperidone 10 mg
  • Roux-Ocefa Laboratorios
  • Motilium
  • Drops; Oral; Domperidone 10 mg / ml
  • Granules, Effervescent; Oral; Domperidone 10 mg
  • Injectable; Injection; Domperidone 2 mg / ml
  • Injectable; Injection; Domperidone 5 mg / ml
  • Suppositories; Rectal; Domperidone 10 mg
  • Suppositories; Rectal; Domperidone 30 mg
  • Suppositories; Rectal; Domperidone 60 mg
  • Suspension; Oral; Domperidone 5 mg / 5 ml
  • Syrup; Oral; Domperidone 5 mg / 5 ml
  • Tablets, Film-Coated; Oral; Domperidone 10 mg
  • Tablets, Orally Disintegrating; Oral; Domperidone 10 mg
  • Tablets; Oral; Domperidone 10 mg
  • Janssen
  • Altana Pharma
  • Catalent
  • DKSH
  • Doncaster Pharmaceuticals Group
  • Dr. Esteve Laboratorios
  • Four Star
  • Johnson & Johnson
  • Landmark Pharma
  • Ortho McNeil Pharmaceuticals
  • Medicem
  • NeoFarma Pharmaceuticals
  • S & M Medical
  • Pharmaghreb Laboratoires
  • Sanofi-Aventis
  • S.C. Terapia
  • Takeda Pharmaceutical
  • The Glory Medicina
  • Winthrop Pharmaceuticals
  • Zentiva
  • Zuellig Pharma
  • Motilium Lingual
  • Tablets; Sublingual; Domperidone 10 mg
  • Janssen
  • Motinorm
  • Drops; Oral; Domperidone 1 mg / ml
  • Suppositories; Rectal; Domperidone 10 mg
  • Suppositories; Rectal; Domperidone 30 mg
  • Suppositories; Rectal; Domperidone 60 mg
  • Suspension; Oral; Domperidone 5 mg / 5 ml
  • Syrup; Oral; Domperidone 5 mg / 5 ml
  • Tablets, Dispersible; Oral; Domperidone 10 mg
  • Tablets; Oral; Domperidone 10 mg
  • Tablets; Oral; Domperidone 30 mg
  • Medley Pharmaceuticals
  • Ambica International Trading Corporation
  • GlaxoSmithKline
  • Royal Distribution
  • Sharif Pharmaceuticals
  • Suprakare
  • Nauzelin
  • Granules, Effervescent; Oral; Domperidone 10 mg
  • Powder for Syrup; Oral; Domperidone 10 mg
  • Suspension; Oral; Domperidone 5 mg / 5 ml
  • Tablets; Oral; Domperidone 5 mg
  • Tablets; Oral; Domperidone 10 mg
  • Janssen
  • Kyowa Hakko
  • Vomistop
  • Drops; Oral; Domperidone 1 mg / ml
  • Drops; Oral; Domperidone 5 mg / ml
  • Suspension; Oral; Domperidone 5 mg / 5 ml
  • Tablets, Dispersible; Oral; Domperidone 10 mg
  • Tablets, Film-Coated; Oral; Domperidone 10 mg
  • Tablets; Oral; Domperidone 10 mg
  • Tablets, Sustained Release; Oral; Domperidone 30 mg
  • Cipla
  • Danas Pharmaceuticals
  • Gracia Pharmindo



  • References:

  • Domperidone main article on Wikipedia: https://en.wikipedia.org/wiki/Domperidone
  • Domperidone compound on PubChem: https://pubchem.ncbi.nlm.nih.gov/compound/Domperidone
  • Domperidone medicine on DrugBank: https://go.drugbank.com/drugs/DB01184
  • Domperidone containing drugs on Drugs-About.com: https://drugs-about.com/ing/domperidone.html
  • Domperidone for sale on Pharma Doctor: https://pharma-doctor.com/domperidone.html
  • Motilium (Domperidone) 10 mg film-coated tablets prescribing information from MedSafe (revised 19 November 2020): https://www.medsafe.govt.nz/profs/Datasheet/m/motiliumtab.pdf
  • Motilium (Domperidone) 10 mg tablets product information from The Therapeutic Goods Administration (revised 04 September 2020): https://www.ebs.tga.gov.au/ebs/picmi/...
  • Motilium (Domperidone) tablets consumer medicine information from The Therapeutic Goods Administration (revised August 2020): https://www.ebs.tga.gov.au/ebs/picmi/...
  • Motilium (Domperidone) 10 mg film-coated tablets summary of product characteristics from Medicines.org.uk (revised 11/09/2020): https://www.medicines.org.uk/emc/product/4177/smpc
  • Motilium (Domperidone) 10 mg film-coated tablets package information leaflet on Medicines.org.uk (revised March 2020): https://www.medicines.org.uk/emc/files/pil.4177.pdf

    Revised: August 2021



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